Biomimetic synthesis and structural revision of tridachiahydropyrone
Version 2 2024-03-12, 21:25Version 2 2024-03-12, 21:25
Version 1 2023-10-19, 21:06Version 1 2023-10-19, 21:06
journal contribution
posted on 2024-03-12, 21:25authored byPallavi Sharma, Nicholas Griffiths, John E. Moses
A short synthesis of the revised structure of the marine natural product tridachiahydropyrone is described. A novel biomimetic photochemicalelectrocyclization was employed to construct the bicyclic carbon framework from an open-chain polyene precursor. The spectroscopic datamatched that of the isolated natural product, supporting a revised structure of this complex metabolite.